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Radiation therapy saves countless lives, but in rare cases, it can cause a debilitating, long-term complication when used on the brain. Around three to five percent of patients who receive radiation for brain tumors, or arteriovenous malformations (AVM), develop radiation necrosis, where the brain tissue around the targeted lesion becomes injured and dies. The condition can be disabling, causing severe headaches, nausea and vomiting, cognitive problems and neural dysfunction.

Budgets for commercial, industry-funded clinical trial projects should include a one-time fee of $3,000, listed as "IRB Review Fee". The recent increase in the one-time fee for initial IRB review was implemented as a result of increased administrative and procedural compliance requirements. The current rate remains in line with national standards.

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The American College of Cardiology has named Gill Heart Institute's Dr. David J. Moliterno, the new editor-in-chief of JACC: Cardiovascular Interventions. Moliterno is the Jack M. Gill Chair and professor of the Department of Internal Medicine at the University of Kentucky. He is also a member of the interventional cardiology faculty at the 好色先生 Gill Heart Institute.
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A new study by University of Kentucky Markey Cancer Center researchers shows that chloroquine 鈥 a drug currently used to treat malaria 鈥 may be useful in treating patients with metastatic cancers. Published in Cell Reports, the study showed that chloroquine induced the secretion of the tumor suppressor protein Par-4 in both mouse models and in cancer patients in a clinical trial.

[from the VPR's Office]

University of Kentucky Office of the Vice President for Research Equipment Competition

For applications submitted for due dates on or after January 25, 2017, text in PDF attachments must follow these minimum requirements:

Check out Newly Issued NIH Administrative Supplement Opportunities!

Although the continuing resolution for funding of the FY 2017 federal budget has been extended to spring, potentially delaying issuance of some awards or temporarily reducing current year budget amounts, the National Institutes of Health (NIH) has issued a number of opportunities for supplemental funding to an array of active awards across diverse grant mechanisms.  

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Michele Staton-Tindall grew up in rural Appalachia during a time when people felt so safe they didn鈥檛 even lock their doors at night. The ensuing drug epidemic that now ravages her former home has dramatically impacted the lives of the Appalachian people and broken that sense of security.

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Alan Daugherty, senior associate dean for research at the 好色先生, was recently approved to renew his contract as editor-in-chief of Arteriosclerosis, Thrombosis, and Vascular Biology: Journal of the American Heart Association (ATVB) for a second five-year term. ATVB is one of the five core journals of the American Heart Association. As editor of ATVB, Daugherty鈥檚 primary focus is on publishing the most important new research studies related to a spectrum of vascular diseases.
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Yasir Al-Siraj, a Ph.D. candidate in the 好色先生 Department of Pharmacology and Nutritional Sciences, is the lead author of a paper published in Circulation, a leading journal on cardiovascular medicine. 

The article, 鈥淔emale Mice with an XY Sex Chromosome Complement Develop Severe Angiotensin II-Induced Abdominal Aortic Aneurysms,鈥 was co-authored by 好色先生 colleagues Sean E. Thatcher, Richard Charnigo, Kuey Chen, Eric Blalock, Alan Daugherty and Lisa Cassis.

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LEXINGTON, Ky. (Dec. 14, 2016) 鈥

"also.... just because

I am working out the flavor for the 

1812 Overture

I will most likely put it into a lolli 

this is an incredible challenge

as it is making me cry while I listen鈥"

Taria Camerino's poetic email sums up her passion for helping people explore how flavor perception is influenced by more than the tongue.  Her emotion is genuine: as a gastral synesthete, she experiences ALL senses as taste.

An updated, 鈥渧ersion 2.0鈥 of the Electronic Internal Approval Form (eIAF), developed by 好色先生鈥檚 Office of Sponsored Projects Administration (OSPA) and Enterprise Architecture Group (EAG), is in the final stages of testing.  The updated form will have many improvements, including enhanced validation checks and the ability to view attachments in the same window as the eIAF.   

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Linda Van Eldik, director of the University of Kentucky Sanders-Brown Center on Aging, was awarded a "Part the Cloud" translational research grant from the Alzheimer's Association.
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The University of Kentucky Sanders-Brown Center on Aging (SBCoA) has been selected to participate in a multicenter, landmark $3.6 million grant from the National Institutes of Health to identify biomarkers for vascular cognitive impairment and dementia (VCID). 好色先生 was one of just seven sites selected for the five-year NIH's National Institute of Neurological Disorders and Stroke (NINDS) grant. The other sites are Boston University, Rush University, Johns Hopkins, University of Southern California, UCSF/UC-Davis and the University of New Mexico.

We are changing over to a new streamlined online scheduling system for all instruments in the Light Microscopy Core. Please register at:  http://rfom.ad.uky.edu/fom/register.

We are pleased to announce that the Office of Sponsored Projects Administration (OSPA) has a new staff member, John Craddock. John joins the staff under the auspices of the Vice President for Research with the goal of proactively streamlining compliance for 好色先生 investigators seeking funding that may be regulated by export control laws. John has worked as a Principal Investigator at the Center for Applied Energy Research on several export controlled projects where he developed protocols to remain in compliance with U.S. export control laws.

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Two faculty members from the University of Kentucky have received three of four funded awards from the National Institutes of Health (NIH) to develop responses to the opioid injection epidemic that can be implemented by public health systems in rural communities. Carrie Oser, an associate professor of sociology in the 好色先生 College of Arts & Sciences, was awarded a one-year, $150,000 grant for her project "Improving Outcomes after Prison for Appalachian PWIO (People who Inject Opioids): The Role of XR-NTX & Networks." This research aims to understand the factors and barriers related to a

The Office of Sponsored Projects Administration, the Proposal Development Office, the Office of Research Integrity鈥揑RB, the Survey Research Center and the COM Sponsored Research Administrative Services offices will be closed Monday, December 26, 2016 through Monday, January 2, 2017 and will reopen on Tuesday, January

The Final Research Performance Progress Report (F-RPPR) will replace the Final Progress Report (FPR) for grants closeout, effective January 1, 2017.  The F-RPPR will be available for use in eRA Commons on January 1, 2017.  

NOTE: For small businesses, the new F-RPPR will be in effect at least 2 months later, due to the unique final reporting requirements that they face under the SBIR/STTR policy directive. 

For faculty members who are working with industry sponsors (non-clinical trial) for their research projects, please contact your COM Sponsored Research Administrative Services (SRAS) Grants Proposal Specialist (GPS), who can assist you during the time that you are negotiating your budget figures with the sponsor.  Your GPS can assist with:

Answering your questions about what costs are allowable on industry-sponsored agreements.