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The University of Kentucky Markey Cancer Center and Leukemia and Lymphoma Society (LLS) recently hosted their eighth annual 鈥淢eet the Researchers鈥 Day. This event is a field trip given as a prize to two schools in the region who successfully raised more than $1,000 for the LLS鈥檚 Pennies for Patients campaign.

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The University of Kentucky Markey Cancer Center celebrated 10 years of Markey Research Day this past Tuesday. Sponsored by the Markey Cancer Foundation, Markey Research Day is an opportunity for researchers who study any aspect of cancer to share their work and receive feedback from colleagues across campus. Markey鈥檚 reach extends across 10 of 好色先生鈥檚 16 colleges, and the work on display at Research Day showcases the wide variety and diversity of perspectives that fall under the Markey umbrella. 

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This week, the University of Kentucky Board of Trustees approved 16 University Research Professorships for the 2019-20 academic year.

The purpose of the University Research Professorship program is to recognize and publicize research accomplishments of scholars across the full range of disciplines at 好色先生. The award amount is $10,000 for one year, to be used to further the research, scholarship and creative endeavors of the awardee.  

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In the past, using the terms "Alzheimer鈥檚 disease" and "dementia" interchangeably was a generally accepted practice. Now there is rising appreciation that a variety of diseases and disease processes contribute to dementia.

According to Nina Silverberg, Ph.D., director of the Alzheimer's Disease Centers Program at National Institute on Aging (NIA), part of NIH, in the past many of the people who enrolled in clinical trials for Alzheimer's drugs likely did not have amyloid 鈥 the sticky substance that gums up neurons and interferes with thinking 鈥 in their brains.  

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The NIH Center of Biomedical Research Excellence (COBRE) on Obesity and Cardiovascular Diseases, in collaboration with the Center for Clinical and Translational Sciences (CCTS) announce the availability of limited funds to support pilot projects focused on research examining obesity-associated diseases. Emphasis for support will be placed on pilot projects that examine the relationship between obesity and cardiovascular diseases, type 2 diabetes, cancer, or neurodegenerative diseases.  These pilot grants are intended to assist investigators new to this area of research

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After being revived with Naloxone in the emergency room, patients immediately enter withdrawal. Cold chills, vomiting, diarrhea 鈥 鈥渄ope sickness鈥 is what many call it. The feeling is hard to describe, but many people who鈥檝e experienced it or witnessed it say it鈥檚 like the worst flu times 10.

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In the largest grant ever awarded to the University of Kentucky, researchers from 好色先生's Center on Drug and Alcohol Research (CDAR) and across campus 鈥 in partnership with the Kentucky Cabinet for Health and Family Services and the Justice and Public Sa

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Mark Williams, MD, Chief Quality and Transformation Officer at 好色先生 HealthCare and Director of the University of Kentucky Center for Health Services Research, and Jing Li, MD, MS, Associate Director of the 好色先生 Center for Health Services Research, presented the findings from Project ACHIEVE at the National Care Transitions Awareness (NCTA) Day Summit, which was held on NCTA Day, April 16.

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Alzheimer's disease wreaks emotional havoc on patients, who are robbed of their memories, their dignity, and their lives.  It鈥檚 financially devastating as well: care for Alzheimer's patients is predicted to top $1 trillion by about the time children born today are having children of their own.

To date, there have been very few successes in the pursuit of a treatment. But one drug that looks at Alzheimer's Disease (AD) from a different angle is now ready for its first round of testing in humans.

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It's an irrefutable fact that smoking is bad for you. Study after study has proven that smoking increases your risk for cancer, heart disease, diabetes 鈥 even blindness.

But dementia? Not so fast. A recent study has demonstrated that smoking is not associated with a higher risk of dementia. 

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Through a recent five-year, $2.3 million grant from the National Institutes of Health (NIH), University of Kentucky faculty Don Frazier and Brett Spear will partner with faculty from qualified minority-serving institutions across the U.S. and Puerto Rico to help improve diversity in science and health care. 

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As a longtime pathologist at the University of Kentucky, Dr. Charles Lutz is no stranger to cancer.

Lutz has spent much of his career in the lab, helping patients behind the scenes. At the 好色先生 Markey Cancer Center, he works in molecular diagnosis and HLA tissue typing in bone marrow transplantation for leukemia and other cancers. He also helps match patients in end-stage organ failure with an appropriate solid organ transplant for the 好色先生 Transplant Center.

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As a raft of new treatments for HIV infection have come on the market in the past 20 years, AIDS patients have gotten access to drugs that allow them to live longer.

"These drugs are miracles," said Dr. Richard N. Greenberg, an infectious disease specialist at the University of Kentucky. "Before the advent of anti-retroviral drugs, HIV infection was a death sentence. Now, taken properly, the life span of a person with an HIV infection is practically normal."

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Regeneration is one of the most enticing areas of biological research. How are some animals able to regrow body parts? Is it possible that humans could do the same? If scientists could unlock the secrets that confer those animals with this remarkable ability, the knowledge could have profound significance in clinical practice down the road.  

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University of Kentucky researchers have identified a potential cellular mechanism that connects a mother's smoking while pregnant with an increased risk in the offspring's obesity later in life. 

Obesity is considered an epidemic in the U.S., with nearly 35 percent of adults and 20 percent of children six to 19 years old deemed obese. Obesity is a serious economic burden as well: more than $150 billion is spent annually on obesity-related healthcare costs in the U.S. alone.

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If staying engaged in something you love is the key to staying young, University of Kentucky emeritus faculty member Don Frazier certainly is on the right track.

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As a child, Chris Waters was always curious about how things worked. His inquiring mind led him on a path from chemical engineering to biomedical engineering to his current work on a dangerous condition called acute respiratory distress syndrome (ARDS).

The mortality rate for this acute lung injury is high 鈥 almost 40 percent of ARDS patients die. Appropriate mechanical ventilation makes a huge difference in their prognosis. 

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University of Kentucky Markey Cancer Center researcher Daret St. Clair, Ph.D., has been named the 2018 Lifetime Achievement Award Recipient from the Society for Redox Biology and Medicine (SfRBM). St. Clair received the award and gave a feature lecture at the SfRBM鈥檚 25th Annual Conference in Chicago earlier this month.

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Researchers at the University of Kentucky have discovered new biological processes by which mutations in the FUS gene cause neurodegeneration in amyotrophic lateral sclerosis (ALS).

FUS is a DNA and RNA binding protein that resides predominantly in the nucleus and appears to play a role in DNA repair and RNA metabolism. In contrast, ALS-related mutations cause the protein to accumulate in the cytoplasm, which can contribute to inclusion bodies 鈥 the pathological hallmarks of disease 鈥 and neurotoxicity.