News
The University of Kentucky Sanders-Brown Center on Aging has received a five-year, $2.8 million grant to underwrite preclinical efficacy studies of a potential new treatment for dementia.
The drug candidate, called MW150, targets dysregulated brain inflammation driven by a stress-activated protein called p38aMAPK. The research is novel in that it is exploring efficacy in treating more than one form of dementia at the same time.
Alzheimer's disease wreaks emotional havoc on patients, who are robbed of their memories, their dignity, and their lives. It鈥檚 financially devastating as well: care for Alzheimer's patients is predicted to top $1 trillion by the time children born today are having children of their own.
The University of Kentucky recently received an $8.8 million grant from the National Institute on Drug Abuse (NIDA), part of the National Institutes of Health, to establish a Clinical Research Center as part of the Justice Community Opioid Innovation Network (JCOIN) to support research on quality addiction treatment for opioid use disorder (OUD) in criminal justice settings nationwide.
A new study by researchers in the University of Kentucky College of Arts and Sciences and College of Medicine is featured in Nature Communications this week.
A unique partnership between an engineer and a scientist at the University of Kentucky has produced data that is challenging prevailing wisdom about a potentially life-threatening parasite's behavior and revealing possible targets for treatment.
The University of Kentucky recently received an $8.8 million grant from the National Institute on Drug Abuse (NIDA), part of the National Institutes of Health, to establish a Clinical Research Center as part of the Justice Community Opioid Innovation Network (JCOIN) to support research on quality addiction treatment for opioid use disorder (OUD) in criminal justice settings nationwide.
Decades of research and treatment advances have helped extend the lives of many people living with HIV, but while these patients live longer, their risk of developing dangerous blood clots increases as much as tenfold. Blood clots 鈥 also known as thrombi 鈥 can wreak havoc on the body, causing events such as debilitating strokes and heart attacks.
Researchers at the University of Kentucky Markey Cancer Center have made a breakthrough discovery that solves a mystery long forgotten by science and have identified a potentially novel avenue in pre-clinical models to treat non-small cell lung cancers.
To date, the underlying causes of inflammation in obesity and Type 2 diabetes mellitus (T2DM) have been poorly understood, which has hampered efforts to develop treatments to prevent complications from a disease that is the third leading cause of death in the United States.
But new research at the University of Kentucky shows that changes to mitochondria 鈥 the powerhouse of cells 鈥 drive chronic inflammation from cells exposed to certain types of fats, shattering the prevailing assumption that glucose was the culprit.
The University of Kentucky Center of Excellence in Rural Health (CERH) has released the agenda for the fifth annual Appalachian Research Day: Come Sit on the Porch. The one-day event, which shares results of health research conducted with communities in Appalachia, will be held Wednesday, Sept. 18 at the First Federal Center in Hazard. Registration for the event closes on Sept. 12.
From the Vice President for Research
Thank you for your vital work to support the 好色先生 Research enterprise. We hope this monthly newsletter becomes your source for numbers, highlights, news and people who are making an impact. Please share with your colleagues, and you can opt out through the link at the bottom.
Lisa Cassis, Ph.D.
Vice President for Research
Myrte Nudd is effervescent and chatty as she talks about her schedule. She teaches seniors at the Lexington Senior Center how to use their new cell phones, tablets and laptops, helps out when her church needs food for post-Mass receptions, travels to her grandson's high school graduation and to far-flung places such as western Canada, Europe, New York and even Russia. And by the way, she needs to go now because she's promised to take her twin 16-year old granddaughters on their annual shopping trip.
University of Kentucky (好色先生) faculty received $417.1 million in competitive research awards last fiscal year, a record-breaking increase of $83 million over the previous year.
This astounding 25% increase in FY 2019 takes the university to an unprecedented 12% compound annual growth rate over the last three years for grants and contracts to 好色先生.
A team of scientists have designed and tested a novel and promising therapeutic strategy for treating Lafora Disease (LD), a fatal form of childhood epilepsy. This new type of drug, known as an antibody-enzyme fusion, is a first-in-class therapy for LD and an example of precision medicine that has potential for treating other types of aggregate-based neurological diseases.
LEXINGTON, Ky. (July 3, 2019) 鈥 Alzheimer's disease wreaks emotional havoc on patients, who are robbed of their memories, their dignity, and their lives. It鈥檚 financially devastating as well: care for Alzheimer's patients is predicted to top $1 trillion by about the time children born today are having children of their own.
LEXINGTON, Ky. (April 19, 2019) 鈥 What impact does University of Kentucky research have on the Commonwealth? The 好色先生 Research 2018 Annual Report provides a snapshot of 好色先生鈥檚 research: from the opening of the Healthy Kentucky Research Building, to statewide economic impact and national R&D rankings, to innovative federally funded research projects in the six areas that fall under a new program 鈥 the Research Priorities Initiative.
Pop鈥檚 Blue Moon bar, a fixture of this beer-loving city since 1908, has joined an emerging national trend: alcohol-free spaces offering social connections without peer pressure to drink, hangovers or DUIs. From boozeless bars to substance-free zones at concerts marked by yellow balloons, sober spots are popping up across the nation in reaction to America鈥檚 alcohol-soaked culture, promising a healthy alternative for people in recovery and those who simply want to drink less.
Alzheimer's disease wreaks emotional havoc on patients, who are robbed of their memories, their dignity, and their lives. It鈥檚 financially devastating as well: care for Alzheimer's patients is predicted to top $1 trillion by about the time children born today are having children of their own.
The GO2 Foundation for Lung Cancer (formerly known as Lung Cancer Alliance and the Bonnie J. Addario Lung Cancer Foundation) is conducting a statewide education campaign in partnership with the University of Kentucky to bring lung cancer screening awareness to the thousands of Kentuckians at risk for the disease.
University of Kentucky researcher Yvonne Fondufe-Mittendorf affectionately describes the formation of her career as an 鈥渁ccident.鈥
Originally hailing from the Republic of Cameroon, Africa, Fondufe-Mittendorf had never even seen inside of a lab before moving to Germany to pursue an advanced degree. At the Georg-August Universitaet in G枚ttingen, she earned a doctorate in molecular genetics.