News

Cardiovascular Science Program Receives $1.2 Million
The National Institutes of Health has renewed a 5-year, $1.2 million grant to the University of Kentucky to help prepare clinical scholars for leadership positions in cardiovascular research. The 好色先生 Training Program for Clinical Scholars in Cardiovascular Science prepares clinical and postdoctoral fellows in medicine, nursing and pharmacy to assume leadership positions directing multidisciplinary research in the field of cardiovascular medicine. "The University of Kentucky has invested substantial resources to develop a highly collaborative training environment that leverages our strength
Vandsburger Elected to NMR in Biomedicine Editorial Advisory Board

The Saha Cardiovascular Research Center鈥檚 Moriel Vandsburger, Ph.D., was elected Associate Member of the NMR in Biomedicine Editorial Advisory Board in recognition of his early-career contributions.

Guo publishes findings that Hepatic SR-BI protects against sepsis in mice

Hepatic scavenger receptor BI protects against polymicrobial-induced sepsis through promoting LPS clearance in mice. Guo L, Zheng Z, Ai J, Huang B, Li XA. J Biol Chem. 2014 Apr 9. [Epub] PMID: 24719333

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Thompson Publishes Findings About Increased Atherosclerosis in Mice

Increased atherosclerosis in mice with increased vascular biglycan content. Thompson JC, Tang T, Wilson PG, Yoder MH, Tannock LR. Atherosclerosis. 2014 Apr 15;235(1):71-75. doi: 10.1016/j.atherosclerosis.2014.03.037. [Epub] PMID: 24816040

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Sui Finds Bisphenol A Increases Athersclerosis in Mouse Model

Bisphenol A Increases Atherosclerosis in Pregnane X Receptor-Humanized ApoE Deficient Mice. Sui Y, Park SH, Helsley RN, Sunkara M, Gonzalez FJ, Morris AJ, Zhou C. J Am Heart Assoc. 2014 Apr 22;3(2):e000492. doi: 10.1161/JAHA.113.000492. PMID: 24755147

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Xiang's Research Shows that Platelets Inhibit Inflammation to Protect from Septic Shock

Platelets protect from septic shock by inhibiting macrophage-dependent inflammation via the cyclooxygenase 1 signalling pathway. Xiang B, Zhang G, Guo L, Li XA, Morris AJ, Daugherty A, Whiteheart SW, Smyth SS, Li Z. Nat Commun. 2013;4:2657. doi: 10.1038/ncomms3657. PMID: 24150174

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Nagareddy Finds Obesity Drives Myelopoiesis

Adipose tissue macrophages promote myelopoiesis and monocytosis in obesity. Nagareddy PR, Kraakman M, Masters SL, Stirzaker RA, Gorman DJ, Grant RW, Dragoljevic D, Hong ES, Abdel-Latif A, Smyth SS, Choi SH, Korner J, Bornfeldt KE, Fisher EA, Dixit VD, Tall AR, Goldberg IJ, Murphy AJ. Cell Metab. 2014 May 6;19(5):821-35. doi: 10.1016/j.cmet.2014.03.029. PMID: 24807222

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Qing Publishes Findings that NOR1聽Inhibits Progenitor Proliferation

Deficiency of the NR4A orphan nuclear receptor NOR1 in hematopoietic stem cells accelerates atherosclerosis. Qing H, Liu Y, Zhao Y, Aono J, Jones KL, Heywood EB, Howatt D, Binkley CM, Daugherty A,  Liang Y, Bruemmer D. Stem Cells. 2014 May 8. doi: 10.1002/stem.1747. [Epub] PMID: 24806827 

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The University of Kentucky Aortic Program Announces the 2014 Aortic Symposium

The University of Kentucky Aortic Program is proud to present the 2014 University of Kentucky Aortic Symposium on Thursday, September 4, - Saturday, September 6 in Lexington, KY. This event will provide a forum for the integration of basic science and clinical care discussions. It will feature talks on aortic aneurysmal diseases from leading experts, as well as abstracts in the form of oral and poster sessions. The Symposium will also include forums for networking that will particularly focus on early career investigations.