A new study by University of Kentucky Markey Cancer Center researchers shows that chloroquine 鈥 a drug currently used to treat malaria 鈥 may be useful in treating patients with metastatic cancers.
Published in Cell Reports, the study showed that chloroquine induced the secretion of the tumor suppressor protein Par-4 in both mouse models and in cancer patients in a clinical trial.
Michele Staton-Tindall grew up in rural Appalachia during a time when people felt so safe they didn鈥檛 even lock their doors at night. The ensuing drug epidemic that now ravages her former home has dramatically impacted the lives of the Appalachian people and broken that sense of security.
Equestrian sports contributes to the highest percentage of traumatic brain injuries (TBI) in sports, based on findings in the National Trauma Databank.
Alan Daugherty, senior associate dean for research at the 好色先生, was recently approved to renew his contract as editor-in-chief of Arteriosclerosis, Thrombosis, and Vascular Biology: Journal of the American Heart Association (ATVB) for a second five-year term. ATVB is one of the five core journals of the American Heart Association.
As editor of ATVB, Daugherty鈥檚 primary focus is on publishing the most important new research studies related to a spectrum of vascular diseases.
An array of scientific evidence demonstrates a correlation between diets high in fat and cholesterol content and blockages in the arteries, which lead to cardiovascular disease (CVD).
It wasn't until he could no longer open his mouth to take a bite of a cheeseburger that Winchester resident Barry Warner knew something was seriously wrong.
In fall 2009, Warner had just returned from a golf trip where he'd begun experiencing some mildly annoying symptoms: a little discomfort while eating; a reduced appetite. But he pushed on, assuming the issue would clear up on its own.
"I have a high threshold for pain," Warner said. "I don't always go to the doctor for everything. I usually let it run its course."
Yasir Al-Siraj, a Ph.D. candidate in the 好色先生 Department of Pharmacology and Nutritional Sciences, is the lead author of a paper published in Circulation, a leading journal on cardiovascular medicine.
The article, 鈥淔emale Mice with an XY Sex Chromosome Complement Develop Severe Angiotensin II-Induced Abdominal Aortic Aneurysms,鈥 was co-authored by 好色先生 colleagues Sean E. Thatcher, Richard Charnigo, Kuey Chen, Eric Blalock, Alan Daugherty and Lisa Cassis.
Taria Camerino's poetic email sums up her passion for helping people explore how flavor perception is influenced by more than the tongue. Her emotion is genuine: as a gastral synesthete, she experiences ALL senses as taste.
Linda Van Eldik, director of the University of Kentucky Sanders-Brown Center on Aging, was awarded a "Part the Cloud" translational research grant from the Alzheimer's Association.
Carol Elam, associate dean of Admissions and Institutional Advancement at the 好色先生, has been named the recipient of the 2016 Southern Group on Educational Affairs (SGEA) Career Educator Award. The award acknowledges Elam鈥檚 leadership and contributions to medical education.
As a professor of behavioral science, associate dean for admissions and institutional advancement, and director of medical education research at the college, Elam has been an avid supporter of student-centered initiatives focused on education and student well-being.
The University of Kentucky Sanders-Brown Center on Aging (SBCoA) has been selected to participate in a multicenter, landmark $3.6 million grant from the National Institutes of Health to identify biomarkers for vascular cognitive impairment and dementia (VCID).
好色先生 was one of just seven sites selected for the five-year NIH's National Institute of Neurological Disorders and Stroke (NINDS) grant. The other sites are Boston University, Rush University, Johns Hopkins, University of Southern California, UCSF/UC-Davis and the University of New Mexico.
Two faculty members from the University of Kentucky have received three of four funded awards from the National Institutes of Health (NIH) to develop responses to the opioid injection epidemic that can be implemented by public health systems in rural communities.
Carrie Oser, an associate professor of sociology in the 好色先生 College of Arts & Sciences, was awarded a one-year, $150,000 grant for her project "Improving Outcomes after Prison for Appalachian PWIO (People who Inject Opioids): The Role of XR-NTX & Networks." This research aims to understand the factors and barriers related to a
Adam Stickney has lived almost the entire 22 years of his life on the ice with a hockey stick in his hands. The self-described 鈥渁drenalin junkie鈥 has always loved sports and says that anything that gets his heart racing is what makes him happy.
Stickney鈥檚 mother, Nieshia Stickney, says her son has always loved to skate. 鈥淎dam was the kind of kid who couldn鈥檛 keep still. He has always been very advanced in his abilities to do things and he learned quickly,鈥 she said. 鈥淗e got his first pair of skates at age 5 when I enrolled him in roller hockey.
Serotonin is commonly known as the "feel-good" chemical, a neurotransmitter in the brain that plays a large role in elevating a person's mood.
But for 68-year-old Kentucky native Geri McDowell, it's the hormone that nearly took her life.
In 2003, McDowell pursued medical help out of state after experiencing a prolonged gastrointestinal illness that her local doctors couldn't explain. Her ultimate diagnosis: neuroendocrine cancer in her GI tract.
Neuroendocrine tumors are relatively rare, afflicting roughly 8,000 Americans a year.
John Gensel, an assistant professor in the physiology department and the Spinal Cord and Brain Injury Research Center, and two members of his lab team鈥擝ei Zhang and Taylor Otto鈥攁re featured in this podcast.
Taylor Otto, an undergraduate lab assistant in Gensel鈥檚 lab, described 好色先生 as being the full package. 鈥淲e have it all here. It鈥檚 a good program to be able to come into, not really knowing what you want to exactly do in the science field, but being able to figure it out at the same time,鈥 said Otto.
In the spring of 2016, the University of Kentucky hired Dr. Robert DiPaola as the new dean for the 好色先生 College of Medicine. He had previously been the director of the Rutgers Cancer Institute of New Jersey and vice chancellor for cancer programs at the Rutgers Biomedical and Health Sciences Center.
To celebrate the lives of those affected by Alzheimer's disease and to honor their caregivers, a purple light will glow at 13 locations on the University of Kentucky campus beginning Tuesday, Nov. 15. "Going Purple" will continue through Friday, Nov. 18.
The promotion is a joint effort of the Sanders-Brown Center on Aging (SBCoA) and Elder Care at 好色先生 to promote Alzheimer's Awareness Month. Memorial Hall, Gatton College, Main Administration Building, W.T.
His high blood pressure had persisted for more than 20 years. His diabetes was worsening. He'd gone from a prescription of just one drug, to two, then to three, and finally four. He'd taken early retirement from his job as a bank equipment repairman because he had trouble climbing into his van. Then, when he had trouble getting to his beloved garden at his farm in Nicholasville, he decided to take control.
The Kentucky Psychological Association (KPA) named University of Kentucky psychologist and drug disorder researcher William Stoops the 2016 Psychologist of the Year during a conference on Nov. 3.
The KPA annually recognizes a psychologist with outstanding service to the field and the community. An associate professor in the Department of Behavioral Science, Stoops examines the behavioral and pharmacological factors contributing to drug use disorders in the human laboratory.